Longevity application
Telomere Lengthening
Telomeres are protective caps on chromosomes that shorten with age. A landmark 2020 study in healthy older adults reported over 20% lengthening of immune-cell telomeres after 60 hyperbaric oxygen sessions — the first human evidence that a therapy could lengthen telomeres. The finding is early and an area of active research.
>20%
Increase in telomere length
Mechanism
HBOT activates telomerase, the enzyme responsible for telomere maintenance and extension. Repeated daily sessions create a hormetic stimulus that upregulates telomerase reverse transcriptase (TERT) expression.
Treatment protocol
Protocol
Pressure
2.0 ATA
Duration
90 min
Sessions
60
Frequency
Once daily, 5×/week
Evidence basis: Hadanny et al., 2020 (RCT)
Key References:
See full citations on the references page.
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