Longevity application
Collagen Production & Skin Health
Hyperbaric oxygen may support skin and connective tissue by stimulating collagen formation. Research shows HBOT increases type III collagen and overall collagen production via growth-factor upregulation, supporting skin elasticity, joint health and connective-tissue integrity. These are early, research-stage findings rather than an established cosmetic treatment.
3×
Increase in collagen III formation
Mechanism
Hyperoxia upregulates VEGF, PDGF, and FGF, promoting fibroblast proliferation and collagen synthesis. HBOT also enhances hydroxylation of proline and lysine residues, critical steps in collagen cross-linking and tissue strength.
Treatment protocol
Protocol
Pressure
2.0 – 2.4 ATA
Duration
90 min
Sessions
20 – 40
Frequency
Once daily, 5×/week
Evidence basis: Clinical Research
Key References:
See full citations on the references page.
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