Longevity application
Cognitive Enhancement
Hyperbaric oxygen has been studied for age-related cognitive change. A randomised controlled trial in healthy older adults reported gains in attention, processing speed, memory and executive function, correlated with increased cerebral blood flow. The findings are encouraging but early-stage; HBOT is not an established treatment for cognitive decline.
16.5%
Improvement in attention & processing speed
Mechanism
HBOT increases regional cerebral blood flow, promotes neuroplasticity through BDNF upregulation, reduces neuroinflammation, and supports hippocampal neurogenesis — all mechanisms diminished with normal aging.
Treatment protocol
Protocol
Pressure
2.0 ATA
Duration
90 min
Sessions
60
Frequency
Once daily, 5×/week
Evidence basis: Hadanny et al., 2020 (RCT)
Key References:
See full citations on the references page.
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