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Infectious Diseases

Refractory Osteomyelitis

Refractory osteomyelitis is a chronic bone infection that persists despite antibiotics and surgery. Hyperbaric oxygen therapy is FDA-approved as an adjunct: it raises oxygen in poorly perfused, infected bone, strengthens the immune cells that clear bacteria, and supports new blood-vessel growth and healing where conventional treatment has stalled.

Evidence Level A Standard of Care

Treatment protocol

Protocol

Pressure

2.0 – 2.4 ATA

Duration

90 min

Sessions

30 – 60

Frequency

Once daily, 5×/week

Evidence basis: UHMS / Standard of Care

References:

See full citations on the references page.

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